PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF GRANGEA MADERASPATANA (L) POIR
DOI:
https://doi.org/10.56588/iabcd.v2i1.141Keywords:
Grangea maderaspatana (L) Poir., phytochemicals, TPC, TFC, TTC, total antioxidantAbstract
This study contributes to a better understanding of Grangea maderaspatana (L) Poir. a species of the Asteraceae family, as a pharmaceutical plant for its phytochemicals. Extracts from leaves analysed for phytochemicals. Methanol and hexane were used to prepare the extracts from the leaf. Spectrophotometric techniques were used to determine the total phenolics, total flavonoids, total tannin and total antioxidants contents. The phytochemical screening was also carried out by means of thin layer chromatography.
References
Ahmed M., Islam M., Hossain C. and Khan O. A preliminary study on the analgesic activity of Grangea maderaspatana. Fitoterapia. 72 (5): 553 – 554 (2001).
Anonymous. The wealth of India. Publication and information Directorate (CSIR, New Delhi, 1985) 126.
Chaturvedi D: Sesquiterpene lactones: Structural diversity and their biological activities. In: Tiwari VK and Mishra BB (eds.): Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry. Research Signpost, Kerala, India, pp313-334, 2011.
German, M. P., De Pasquale, R., Dangelo, V., Catania, S., Silvari, V., & Costa, C. (2002). Evaluation of extracts and isolated fraction from Capparis spinosa L. buds as an antioxidant source. Journal of agricultural and food chemistry, 50(5), 1168-1171.
Harborne, J.B. 1973. Phytochemicals Method. Chapman and Hall Ltd., London, pp. 49-188.
Issiaka Togola, Mamadou Abdoulaye Konaré, Méminata Diakité, Nouhoun Diarra, Fatoumata Tounkara, Rokia Sanogo et al. Evaluation of the total alkaloid content at different stages of development of Datura innoxia Mill, a plant used in traditional medicine in Mali. Am. J. Innov. Res. appl. Science. 2019; 9(2): 200-07.
Iyer C. and Iyer P. Steroids from Grangea maderaspatana Poir. Phytochemistry. 17 (11): 2036 – 2037 (1978).
Jain S., Sareen V. and Narula A. Oestrogenic and pregnancy interceptory efficacy of a flavonoid mixture from Grangea maderaspatana Poir (Artemisia maderaspatana) in the mouse. Phytother Res. 7 (5): 381 – 383 (1993).
Kamtekar, S., Keer, V., & Patil, V. (2014). Estimation of phenolic content, flavonoid content, antioxidant and alpha amylase inhibitory activity of marketed polyherbal formulation. Journal of applied pharmaceutical Science, 4(9), 061-065.
Krishna V. and Singh P. A clerodane derivative from Grangea maderaspatana, Phytochemistry. 52: 1341 – 1343 (1999).
Krishna V. and Singh P. Highly oxygen flavonoids from Grangea maderaspatana. J. Medicinal Aromatic Plant Sci. 23 (4): 609 – 611 (2002).
Liu, F., Sun, C., Yang, W., Yuan, F., & Gao, Y. (2015). Structural characterization and functional evaluation of lactoferrin–polyphenol conjugates formed by free-radical graft copolymerization. RSC advances, 5(20), 15641-15651.
Malik K, Ahmad M, Bussmann R.W, Tariq A, Ullah R, Alqahtani A.S, Shahat A.A, Rashid N, Zafar M, Sultana S. and Shah S.N. 2018. Ethnobotany of antihypertensive plants used in northern Pakistan. Front. Pharmacol, 9, p.789.
Nadkarni A. Indian material medica, Volume- I, (Popular prakashan, Bombay 1976) 592.
Opitz, S. E., Smrke, S., Goodman, B. A., & Yeretzian, C. (2014). Methodology for the measurement of antioxidant capacity of coffee: A validated platform composed of three complementary antioxidant assays. In Processing and Impact on Antioxidants in Beverages (pp. 253-264). Academic Press
Pati, P. K., Sharma, M., Salar, R. K., Sharma, A., Gupta, A. P., & Singh, B. (2008). Studies on leaf spot disease of Withania somnifera and its impact on secondary metabolites. Indian journal of microbiology, 48, 432-437.
Rebaya, A., Belghith, S. I., Baghdikian, B., Leddet, V. M., Mabrouki, F., Olivier, E., ... & Ayadi, M. T. (2015). Total phenolic, total flavonoid, tannin content, and antioxidant capacity of Halimium halimifolium (Cistaceae). Journal of applied pharmaceutical science, 5(1), 052-057.
Ruangrungsi N., Kasiwong S., Likhitwitayawuid K., Lange G. and Decicco C. Constituents of Grangea maderaspatana: A new eudesmanolide. J Natural Products. 52 (1): 130 – 134 (1989).
Singh P. and Jain S. Auranamide – A phenylalanine derivative from Grangea maderaspatana Poir. J Ind Chem Soc Int. 67 (7): 596 – 597 (1990).
Singleton, V. L., & Rossi, J. A. (1965). Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. American journal of Enology and Viticulture, 16(3), 144-158.
Ullah R, Alqahtani A.S, Noman O.M, Alqahtani A.M, Ibenmoussa S. and Bourhia M. A review on ethno-medicinal plants used in traditional medicine in the Kingdom of Saudi Arabia. Saudi J. Biol. Sci. 2020 ;27(10) :2706-2718.
Ullah R, Alsaid M.S, Alqahtani A.S, Shahat A.A, Naser A.A, Mahmood H.M, Ahamad S.R, Al-Mishari A.A. and Ahmad S., 2019. Anti-inflammatory, antipyretic, analgesic, and antioxidant activities of Haloxylon salicornicum aqueous fraction. Open Chem., 17(1), pp.1034-1042.
Yen, G. C., & Duh, P. D. (1994). Scavenging effect of methanolic extracts of peanut hulls on free-radical and active-oxygen species. Journal of agricultural and food chemistry, 42(3), 629-632.6
