International Association of Biologicals and Computational Digest

A STUDY OF ACHIEVEMENT MOTIVATION AND ANXIETY AMONG THE CHILDREN OF WORKING AND NON-WORKING WOMEN

2024-03-13T10:04:30+00:00

The aim of the present study is to investigate the effects of achievement motivation (AM) and anxiety (AN) on the children of working and non-working women. These kids are in high school. A random sample of 10 secondary schools in the city of Ahmedabad was selected for this study. A unit of 250 children was selected for data collection, of which 90 were working children and 160 were non-working women. The resulting analysis showed that the children of working women were more affordable than the children of non-working women. Moreover, there is a significance difference between the anxiety of working and non-working women’s children. After the analysis of anxiety of working and non-working women’s children, girls of working women showed the highest anxiety. These may be associated with some reasons, like girls have to share part of their women responsibility and the girls working women do not get required attention, guidance and care during their formative period.

PHYTOCHEMICAL ANALYSIS OF EUPHORBIA SPECIES OF GUJARAT, INDIA: A REVIEW

2023-12-21T14:04:15+00:00

In India, out of195 species of Euphorbia sub-genus, about 23 species have been recorded in the state of Gujarat, out of which phytochemical work has been done on only 12–13 species. These Euphorbia species have ethnobotanical significance and are used by indigenous communities. The research work on these species has till now displayed the presence of phytochemicals and secondary metabolites like phenolic compounds, flavonoids, tannins, terpenes, terpenoids, cardiac glycosides, etc., which are used in the treatment of skin disorders, arthritis, cancer treatment, cytotoxicity, etc. The purification of the phytochemicals revealed the exact chemical structure of the compounds present, which may help in further research and overlap with fields such as phylogenetics, cell biology, molecular biology, enzymology, etc. There is future scope for research in the investigation of phytochemicals of Euphorbia sp., like E. rosea Retz., E. orbiculate H. B. & K, on which research work has not been conducted yet.

EXPLORING THE ANTI-CANCER POTENTIAL OF PHYTOCHEMICALS FROM SPECIFIC PLANTS: EXAMINING AND VALIDATING THROUGH MOLECULAR DOCKING AND MD SIMULATIONS

2024-03-02T09:28:44+00:00

Worldwide, cancer is the leading cause of death. Anti-cancer medications frequently induce side effects and multidrug resistance (MDR), which continues to be a key obstacle to effective cancer therapy. Essential nutrients and functionally bioactive substances can both be found in abundance in plants. The phytochemical components have great promise for treating both plant and human ailments. This study is designed to conduct an in-silico analysis on phytochemicals derived from Combretaceae family plants for targeting the proteins 4UWH, 5LWM, and 6P3D. The Combretaceae family has demonstrated pharmacological benefits such as anti-leishmanial, cytotoxic, antibacterial, antidiabetic, antiprotozoal, anticancer, and antifungal qualities. To conduct experiments with the natural phytochemicals against the proteins, computerized tools, online servers, and online databases were used. 196 natural compounds were used for virtual screening out of the top 5 best-docked compounds selected based on their binding energy. The best-selected phytochemicals possessed potential results in 10ns molecular dynamic simulation. So, it is convincible based on in-silico research this selected phytochemical has the potential to serve as a promising lead compound against cancer.